Molecular Foundry Seminar

"Nanoparticles in Biology: Engineering the Interface for Delivery and Sensing,"

Professor Vincent Rotello, Department of Chemistry, University of Massachusetts,

Tuesday, March 23rd at 1:30 pm, Room 67-3111

Abstract:

A key issue in the use of nanomaterials is controlling the interfacial interactions of these complex systems. Our research program focuses on the tailoring of interfaces by coupling the atomic-level control provided by organic synthesis with the fundamental principles of supramolecular chemistry. Using these tailored monolayers, we are developing particles for biological applications in particular delivery and sensing. This talk will focus on the interfacing of nanoparticles with biosystems, and will discuss our use of nanoparticles for delivery applications as well as our use of polymer-nanoparticle systems for sensing and identification of proteins, bacteria, and cancer detection/identification of mammalian cells.