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Date: Tuesday, February 4, 2014
Time: 11:00 am
Speaker: Dr. David Baker, University of Washington
Title: Design of Protein Structures, Functions and Assemblies
Location: 67-3111 Chemla Room


Hosted by Ron Zuckermann
Abstract:

I will describe recent advances in computational protein design which allow the generation of new protein structures and functions. I will describe the use of these methods to design ultra-stable idealized proteins, flu neutralizing proteins, high affinity ligand binding proteins, and self assembling protein nanomaterials. I will discuss possible applications to therapeutics, vaccines and diagnostics. I will also describe the contributions of the general public to these efforts through the distributed computing project Rosetta@home and the online protein folding and design game FoldIt.