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Frank Svec: Using Gold to Boost Power of Chromatography

MSD scientist Frantisek Svec, director of the Organic and Macromolecular Synthesis facility at the Molecular Foundry, described a technique for boosting the power of chromatography for separating proteins and peptides. Speaking at the recent national meeting of the American Chemical Society, Svec explained how the addition of gold nanoparticles to the surfaces of polymer monoliths in chromatographs creates a universal ligand that can be used to fish out thiol-containing proteins and peptides and opens new avenues to the functionalization and control of pore surface chemistry. [MORE]