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August 2013

Building Blocks for Biochemists

Scientific Achievement

Researchers have created a flexible, scaled, physical model of a polypeptide chain, which accurately reproduces the bond rotational degrees of freedom in the peptide backbone.

Significance and Impact

The development of this interactive model, called a Peppytide, has the potential for use as an educational aid – for both researches and students – towards the intuitive understanding of chain folding as the basis for macromolecular structure.

Research Details

The Peppytide model features:

P. Chakraborty & R. N. Zuckermann. Proc Natl Acad Sci USA 2013 110, 13368.