« Foundry Home Page

August 2014

Sugar Mimic Leads Stem Cells to Develop into Nerve Cells

Scientific Achievement

Users of the Molecular Foundry created a mimic of proteoglycans – surface-bound sugars – that are critical in the differentiation of embryonic stem cells into neural cells.

Significance and Impact

Since natural sugars are difficult to manage, the development of proteoglycan mimics could significantly decrease the cost and complexity of tissue engineering and stem cell therapy.

Research Details

PM. L. Huang, R. A. Smith, G. W. Trieger, & K. Godula. J Am Chem Soc. 2014 136, 30.