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April 2016

Electron Microscopy Discovers Peptoid Crystalline Nanotubes

Scientific Achievement

Electron micrographs of amphiphilic peptoids in water reveal crystalline nanotubes with exposed hydrophobic groups.

Significance and Impact

The 2.4 nm stripe pattern in the electron micrograph rules out the possibility of micelle formation, establishing a new principle of supramolecular assembly.

Research Details

Sun, J., Jiang, X., Lund , R., Downing, K.H., Balsara, N.P., Zuckermann, R.N., Proc. Natl. Acad. Sci. U.S.A. (2016) doi:10.1073/pnas.1517169113