 Overview
This facility provides instruments
and expertise for Users pursuing theintegration
of biological components into functional nanoscale materials, the
mimicry of biological architectures, and the use of nanotechnologies
to elucidate biological mechanisms. It features biological
techniques in a nanotechnology environment.
Ron
Zuckermann, Facility Director
Biological
Nanostructures Facility Research Program
Instrumentation
• Total internal Reflection Microscopy System
with Olympus IX-81w/Andor EMCCD camera
• Amersham Biosciences Akta
FPLC
• Agilent 1100 series (ion trap) LC-MC-MC Mass
spectrometer
• Beckman NXp High Throughput Screening Robot
• Varian analytical,
semi-prep and prep HPLCs
• CEM Liberty Microwave Peptide Synthesizer
• Biotage SP1 Flash Chromatography System
• Custom-built Robotic Combinatorial Synthesizers
• ACT Apex 396 Peptide Synthesizer
• Total internal Reflection Microscopy System
with Olympus IX-81w/Andor EMCCD camera
• Amersham Biosciences Akta FPLC
• Agilent 1100 series (ion trap) LC-MC-MC Mass
spectrometer
• Beckman NXp High Throughput Screening Robot
• Varian analytical, semi-prep and prep HPLCs
• CEM Liberty Microwave Peptide Synthesizer
• Biotage SP1 Flash Chromatography System
• Custom-built Robotic Combinatorial Synthesizers
• ACT Apex 396
Peptide Synthesizer
• Beckman Optima Ultracentrifuge
• Real-time PCR 7000 Sequence Detection System
• New Brunswick BioFlo 310 Fermentor
• Molecular Devices Absorbance and Fluorescence
Plate Readers
• Jobin Yvon FluoroMax Flourimeter
• Cell culture incubators and biosafety cabinets
Capabilities
• mammalian and microbial cell culture
• protein expression and purification
• biopolymer synthesis (natural and biomimetic)
• biocompatible coating of nanomaterials
• biological imaging using quantum dots
• phage display of peptide libraries
• molecular biology techniques for DNA/RNA manipulations
• genetic engineering of cell lines for materials integration
• combinatorial library synthesis and screening
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