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December 2018

A Peptoid Mimic That Can Bind Multi-metallic Clusters

Scientific Achievement

Foundry staff and users have created a new peptoid design that makes a protein-mimic capable of binding to multi-metallic molecules.

Significance and Impact

This method provides, for the first time, a simple way to build atomically defined, non-natural folded structures that can bind to multi-metallic clusters. The new method will enable researchers to develop biomimetic structures for solar-to-fuel catalysis and to engineer function into artificial structures.

Research Details

A.I. Nguyen, R. K. Spencer, C.L. Anderson, R.N. Zuckermann. Chemical Science. (2018). 9. 8806-8813