A suite of tools for the purification and analysis of small molecules, peptides, peptoids, and proteins.
Zeiss 710 Laser Scanning Confocal Microscope with Upconversion Capabilities and AiryScan detector
Staff Contact: Behzad Rad & Bruce Cohen
Multi-laser scanning confocal system with an additional NIR laser for upconversion. Equipped with 34 PMTs for spectral imaging, femtoinjector for microinjection of single cells, and a fully controlled cell chamber for extended live-cell studies. The LSM710 is upgraded with an attached Airy Scan detector to allow for sub-diffraction imaging. An Eppendorf FemtoInjector is available for live-cell nanoparticle injections.
Analytical HPLC and UPLC
Staff Contact: Michael Connolly & Tasha Molchanova
Varian HPLC and Waters UPLC analytical systems are used to analyze small molecules, peptides, peptoids and proteins produced at the Foundry. These systems are configured for reverse-phase chromatography (C4 and C18).
Preparative HPLC
Staff Contact: Michael Connolly & Tasha Molchanova
The suite of Waters and Varian HPLCs is used to purify small molecules, peptides, peptoids and proteins produced at the Foundry by reverse-phase chromatography (C4 and C18). Typical scale is 1 to 100 mg of product.
Jobin Yvon Fluoromax Fluorimeter
Staff Contact: Behzad Rad & Bruce Cohen
The fluorimeter is a quality spectrophotometer used to characterize the fluorescent properties of compounds/proteins/nanoparticles synthesized.
