Zeiss Libra 120 Cryo-TEM
This microscope is designed for 2D and 3D imaging and characterization of soft materials in a near-native liquid state under liquid nitrogen temperature using cryo-electron microscopy. It is particularly suited for non-averaged 3D reconstruction of an individual biomolecule particles at nanometer resolution. The 120 kV high-tension LaB₆ filament TEM utilizes a low-dose, high-sensitivity 4k × 4k Gatan Ultrascan CCD camera for image acquisition. The column has four pre-installed apertures for imaging at different magnifications and an in-column omega energy filter. The microscope is equipped with both standard Gatan and in-house-developed tomography software for 3D imaging of heterogeneous samples. It can also be used with negatively stained samples for screening soft and biological materials.